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Multimodal Assessment of the Neurological Prognosis of Patients With Brain Lesions on ExtraCorporeal Life Support

NCT03633981 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 50

Last updated 2018-10-16

No results posted yet for this study

Summary

It seems of the greatest importance to evaluate the neurological prognosis of patients with brain lesions after cardiorespiratory arrest or circulatory failure requiring circulatory assistance.

However, to date, there is no clinical or paraclinical diagnostic test to reliably assess the future of these patients.

The objective of this study is to highlight the clinical and imaging factors for establishing a neurological prognosis in patients at risk of brain lesions under ExtraCorporeal Life Support (ECLS).

Conditions

  • Brain-injured Patients on Extracorporeal Life Support

Interventions

OTHER

clinical examinations

Collection of data from the following tests at H0 (as soon as the ECLS is put in place), H12 (within 12 hours following stabilisation of the dynamic state), H24 and every day until complete neurological recovery: * right and left pupillometry (3 times) * BIS values * right and left NIRS values * right and left transcranial Doppler * neurological clinical examination

OTHER

neurological assessment when a neurological event occurs

next neurological event: * seizures * pupillary asymmetry * myoclonias * brain stem reflex abnormalities * osteotendinous reflex abnormalities

OTHER

mortality assessment

to 28 days

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Dijon

    lead OTHER

Principal Investigators

  • Mohamed Omar ELLOUZE · Centre Hospitalier Universitaire Dijon

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2019-09-01
Completion
2019-12-01

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03633981 on ClinicalTrials.gov