Study for the Improvement of Long-Term Outcome Prediction in Patients in Coma After Cardiac Arrest

Summary

The primary objective of HOPE is to improve the accuracy of outcome prediction in anoxic-ischemic encephalopathy following cardiac arrest by bringing under close scrutiny some of the existing methods used for this purpose (e.g. somato-sensory evoked potentials). HOPE is the first multicenter prospective cohort study on coma prognosis to control for the effect of a possible self-fulfilling prophecy at the ICU and to cover the acute and neurorehabilitation phases with a long-term follow-up longer than the usual three or six months.

Conditions

• Anoxic-Ischemic Encephalopathy

Sponsors & Collaborators

• Else Kröner Fresenius Foundation

  collaborator OTHER

• University Hospital Augsburg

  collaborator OTHER

• Klinikum Ingolstadt

  collaborator OTHER

• Klinikum Rosenheim

  collaborator OTHER

• Therapiezentrum Burgau

  collaborator OTHER

• Schoen Clinic Bad Aibling

  collaborator OTHER

• Schön Klinik München Schwabing

  collaborator UNKNOWN

• Asklepios Stadtklinik Bad Tölz

  collaborator UNKNOWN

• Technical University of Munich

  collaborator OTHER

• Krankenhaus Barmherzige Brüder München

  collaborator UNKNOWN

• Roteskreuzklinikum München

  collaborator UNKNOWN

• Deutsches Herzzentrum Muenchen

  collaborator OTHER

• Ludwig-Maximilians - University of Munich

  lead OTHER

Principal Investigators

• Andreas Bender, MD · Ludwig-Maximilians-Universität München

Eligibility

Min Age

18 Years

Max Age

85 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-10-31

Primary Completion

2018-12-06

Completion

2018-12-06

Countries

• Germany

Study Locations