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Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

NCT03593408 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 20

Last updated 2026-01-09

No results posted yet for this study

Summary

This study will measure plasma concentrations of dexmedetomidine, fentanyl, morphine and midazolam in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to understand the pharmacokinetics of these drugs in this setting.

Conditions

  • Drug Effect

Interventions

DRUG

Dexmedetomidine

Administered for sedation management per hospital protocol

DRUG

Fentanyl

Administered for sedation management per hospital protocol

DRUG

Midazolam

Administered for sedation management per hospital protocol

DRUG

Morphine

Administered for sedation management per hospital protocol

Sponsors & Collaborators

Principal Investigators

  • Viviane Nasr, MD · Boston Children's Hospital

Eligibility

Min Age
0 Days
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-02-08
Primary Completion
2026-08-01
Completion
2026-12-01
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03593408 on ClinicalTrials.gov