MedTrace Logo

The Effects of Dexmedetomidine on the Heart Beat During Elective Surgery in Children

NCT02353169 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 64

Last updated 2019-10-07

Study results available
· View outcomes & findings →

Summary

Dexmedetomidine is a sedative drug that is commonly used to improve calmness and reduce pain in children waking up after surgery. Some of the side effects of dexmedetomidine, such as a potential change in how the heart muscles contract and changes in blood sugar and potassium levels, are poorly understood. The current study aims to examine these changes directly in healthy children undergoing elective surgery by measuring the heart beats (with an electrocardiogram) and blood sugar and potassium at specific times before and after dexmedetomidine is given. The investigators aim to establish a better understanding of this drug's safety profile.

Conditions

  • Myocardial Repolarization
  • Healthy

Interventions

DRUG

Dexmedetomidine

DRUG

Saline

Sponsors & Collaborators

  • University of British Columbia

    lead OTHER

Principal Investigators

  • Simon Whyte, MBBS, FRCA · BC Children's Hospital, Department of Anesthesia

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
3 Years
Max Age
10 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-09-30
Primary Completion
2017-09-30
Completion
2017-12-31

Countries

  • Canada

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02353169 on ClinicalTrials.gov