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Pharmacokinetic Analysis of Midazolam and Fentanyl in Pediatric Patients With Long-term Analgosedation

NCT02302391 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 25

Last updated 2021-04-30

No results posted yet for this study

Summary

Pharmacokinetic monitoring of midazolam, it's active metabolite and fentanyl in pediatric patients with long-term analgosedation will be performed. Especially, the chronologic sequence of the quantified plasma levels during sedation and during wake-up as well as the correlation to dose and sedation depth will be focused.

Conditions

  • Deep Sedation
  • Intensive Care Pediatric

Interventions

OTHER

PK analysis

Quantification of Serum Levels and subsequent pharmacokinetic (PK) modelling.

Sponsors & Collaborators

  • Universitätsklinikum Hamburg-Eppendorf

    lead OTHER

Principal Investigators

  • Dominique Singer, Prof. Dr. · University Medical Center Hamburg-Eppendorf, Department of Pediatrics

Eligibility

Min Age
28 Days
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-10-31
Primary Completion
2018-03-31
Completion
2018-10-31

Countries

  • Germany

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02302391 on ClinicalTrials.gov