Fentanyl

Drug

Also known as: Fentanyl Citrate, opioid

Drug Profile

Fentanyl is a potent synthetic opioid analgesic that is far more potent than morphine. It is commonly used clinically for severe pain management and as a sedative or analgesic in perioperative and critical care settings. Fentanyl was first produced in 1960 and approved for use in the United States in 1968.

Drug Class
Synthetic opioid analgesic
Approval Status
Approved for use in the United States in 1968.
Mechanism of Action
Mu-selective opioid receptor agonist that produces analgesia via opioid receptor activation.
Brand Names
  • Sublimaze
  • Actiq
  • Fentora
  • Abstral
  • Lazanda
  • Subsys
  • Duragesic
Indications
  • \Severe pain management in opioid-tolerant patients\
  • \Analgesia before, during, and after surgery\
  • \Anesthesia support (general or regional anesthesia)\

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