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The Interaction Between Oxytocin and Serotonin

NCT03577457 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2018-07-12

No results posted yet for this study

Summary

The primary objective of this study is to identify any interaction between oxytocin and serotonin on neural and behavioral activity related to social reward and decision making by a double-blind, placebo-controlled, between-subject, pharmacological fMRI design

Conditions

  • Healthy

Interventions

DRUG

oxytocin nasal spray

intranasal administration of oxytocin (24 IU)

DRUG

ATD treatment

oral administration of ATD (75.2g) (Acute Tryptophan Depletion)

DRUG

intranasal placebo treatment (placebo-control for oxytocin)

intranasal administration of placebo nasal spray

DRUG

oral placebo treatment (placebo-control for ATD)

oral administration of a tryptophan-balanced mixture (78.2g)

Sponsors & Collaborators

  • University of Electronic Science and Technology of China

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
30 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-02-01
Primary Completion
2019-06-20
Completion
2019-07-20

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03577457 on ClinicalTrials.gov