Effects of Oxytocin on the Functional Architecture of the Brain Before and After Prolonged Naturalistic Fear Induction
NCT05896553 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 69
Last updated 2025-04-04
Summary
The main aim of the pharmacological resting-state fMRI study is to investigate the modulatory effects of intranasal Oxytocin (24IU) on task and intrinsic functional connectivity before and after prolonged exposure to naturalistic fear induction via a movie.
Conditions
- Healthy
Interventions
- DRUG
-
intranasal Oxytocin(24IU)
Administration of intranasal Oxytocin(24IU)
- DRUG
-
intranasal Placebo
Administration of intranasal Placebo
Sponsors & Collaborators
-
University of Electronic Science and Technology of China
lead OTHER
Principal Investigators
-
Benjamin Becker, Dr. · University of Electronic Science and Technology of China
Study Design
- Allocation
- RANDOMIZED
- Purpose
- BASIC_SCIENCE
- Masking
- DOUBLE
- Model
- PARALLEL
Eligibility
- Min Age
- 18 Years
- Max Age
- 30 Years
- Sex
- MALE
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2023-05-29
- Primary Completion
- 2024-04-01
- Completion
- 2024-04-15
Countries
- China
Study Locations
More Related Trials
-
The Effects of Oxytocin on Social Touch
NCT03278860 ·Status: UNKNOWN ·Phase: NA
-
The Interaction Between Oxytocin and Serotonin
NCT03426176 ·Status: UNKNOWN ·Phase: NA
-
Spatial Context and Fear Learning
NCT02423044 ·Status: COMPLETED
-
Oxytocin, Emotions and Mirror Neurons
NCT02228031 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Brain Imaging Changes in Fear and Anxiety
NCT00047853 ·Status: COMPLETED ·Phase: NA
-
The Interaction Between Oxytocin and Serotonin
NCT03577457 ·Status: UNKNOWN ·Phase: NA
-
Ocytocine and Cerebral Activation in Relation With Attachement
NCT02847143 ·Status: COMPLETED ·Phase: PHASE2
-
Neuroimaging Memories of Fear and Safety in the Human Brain
NCT04975009 ·Status: RECRUITING ·Phase: NA
-
Real-time fMRI Neurofeedback Training on the Anterior Insula Based on Interoceptive Processing
NCT05260749 ·Status: COMPLETED ·Phase: NA
-
Oxytocin and Social Cognition in Frontotemporal Dementia
NCT01002300 ·Status: COMPLETED ·Phase: NA
-
Effects of Duloxetine on Pathological Worry in Patients With Generalized Anxiety Disorder: A fMRI Study
NCT00491348 ·Status: TERMINATED ·Phase: NA
-
Neuronal Correlates of Altered States of Consciousness
NCT02308969 ·Status: COMPLETED ·Phase: EARLY_PHASE1
-
Unveiling the Neural Mechanisms of 5-HT7 in Sleep Apnea Induced by Arousal Dysregulation
NCT06608888 ·Status: RECRUITING
-
Neurofeedback Enhanced Cognitive Reappraisal Training - Phase 4
NCT06563310 ·Status: RECRUITING ·Phase: NA
-
The Role of Music Stimulation in Disorders of Consciousness State: an fMRI Study
NCT03492294 ·Status: COMPLETED
-
Vasopressin and Pain Perception in the Brain
NCT03446456 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Brain Imaging Study of Adults With Autism Spectrum Disorders
NCT01093768 ·Status: COMPLETED ·Phase: PHASE1
-
Childhood Trauma and Escape Decision Dynamics
NCT04290234 ·Status: UNKNOWN
-
Compensatory Brain Mechanisms for Amygdala-associated Cognitive Dysfunction: Potential Role of the Cortical Mirror Neuron System
NCT03723733 ·Status: UNKNOWN
-
Individual Differences in Cognitive Control Predict Real-time fMRI Neurofeedback Performance
NCT07211269 ·Status: RECRUITING ·Phase: NA
-
Changes in Brain Activity (Functional MRI Study) Before and After Behavioral Therapy of Height Phobia
NCT00302978 ·Status: COMPLETED ·Phase: NA
-
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
NCT00591825 ·Status: COMPLETED ·Phase: PHASE2
-
Real-time Neurofeedback Training of Fronto-limbic Regions Functional Connectivity
NCT06033053 ·Status: RECRUITING ·Phase: NA
-
Neuroimaging of Anesthetic Modulation of Human Consciousness
NCT03361605 ·Status: COMPLETED ·Phase: PHASE4
-
Real-time NIRS Neurofeedback Regulating Brain Cognitive Function in Obese Individuals
NCT04071717 ·Status: UNKNOWN ·Phase: NA