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Magnesium Sulphate Versus Lidocaine for Control of Emergence Hypertension

NCT03566329 · Status: UNKNOWN · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 90

Last updated 2019-08-15

No results posted yet for this study

Summary

Post-craniotomy emergence hypertension is a common phenomenon that may predispose to development of intracranial hematoma and cerebral edema.The aim of this study is to compare the safety and efficacy of Mgso4 versus lidocaine infusion for control of emergence hypertension after craniotomy.

Conditions

Interventions

DRUG

Magnesium sulphate

Magnesium sulphate 50 mg/kg over 10 minutes loading followed by 15mg/kg/hr infusion. .

DRUG

Lidocaine Hydrochloride

lidocaine hydrochloride 1.5mg/kg loading followed by 2mg/kg/hr infusion

DRUG

Normal saline

Normal saline infusion with the same rate of infusion as the study drugs

Sponsors & Collaborators

  • Ahmed Mohamed ELbadawy

    lead OTHER

Principal Investigators

  • Ahmed ELbadawy, MD · Faculty of medicine- Cairo University- Egypt

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-07-10
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • Egypt

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03566329 on ClinicalTrials.gov