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Gut-brain Axis, Brain Function, and Behaviour.

NCT03554694 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2018-06-13

No results posted yet for this study

Summary

The aim is to test if dietary supplementation with prebiotics reduces measures of anxiety in healthy human participants with high self-reported levels of anxiety. Study will test for an effect on behavioural, neuroendocrine and brain imaging markers of anxiety.

Conditions

  • Prebiotics
  • Anxiety
  • Humans
  • Magnetic Resonance Imaging
  • Decision Making
  • Emotion
  • Cortisol

Interventions

DIETARY_SUPPLEMENT

Prebiotics

Galactooligosaccharides (GOS) (prebiotics) will be consumed by the participants for 4-6 weeks

DIETARY_SUPPLEMENT

Maltodextrin (placebo)

Maltodextrin (placebo) will be consumed by the participants for 4-6 weeks

Sponsors & Collaborators

  • National Health and Medical Research Council, Australia

    collaborator OTHER

  • Oxford Health Biomedical Research Centre (OH BRC) support scheme

    collaborator UNKNOWN

  • Wellcome Centre for Integrative Neuroimaging

    collaborator UNKNOWN

  • Monash University

    collaborator OTHER

  • University of Oxford

    lead OTHER

Principal Investigators

  • Jacinta O'Shea, PhD · University of Oxford

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2018-05-06
Primary Completion
2019-12-31
Completion
2019-12-31

Countries

  • United Kingdom

Study Locations

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Diseases
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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03554694 on ClinicalTrials.gov