MedTrace Logo

Effects of Prebiotics on Intestinal Colonization and Mood in a University Cohort

NCT05212545 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 96

Last updated 2022-12-20

No results posted yet for this study

Summary

There is a growing interest within the scientific community of whether prebiotics can aid in clinical outcomes including mood via modulation of the gut microbiota and its resulting metabolites via the gut-brain axis. This is especially prevalent given that mental health conditions are associated with cost and burden on the health care system. Yet, to date very few studies have investigated the potential effects of prebiotics to influence mood via the modulation of the gut microbiota with previous studies recording mixed results indicating further work in this area would be highly beneficial.

Conditions

  • Mood

Interventions

DIETARY_SUPPLEMENT

Placebo

maltodextrin taken daily for 4 weeks with water

DIETARY_SUPPLEMENT

Prebiotic supplement

Prebiotic supplement taken daily for 4 weeks with water

DIETARY_SUPPLEMENT

Prebiotic combination

prebiotic oligosaccharides mixture taken daily for 4 weeks with water

DIETARY_SUPPLEMENT

Prebiotic oligosaccharides

Prebiotic oligosaccharides taken daily for 4 weeks with water

Sponsors & Collaborators

  • University of Reading

    collaborator OTHER

  • Beneo-Institute

    lead INDUSTRY

Principal Investigators

  • Robert A Rastall, Prof · University of Reading

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2022-01-12
Primary Completion
2022-06-30
Completion
2022-09-19

Countries

  • United Kingdom

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05212545 on ClinicalTrials.gov