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Probiotics and the Gut Brain Axis- Do Probiotics Interact With the Vagal Nerve?

NCT04772664 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 86

Last updated 2024-03-15

No results posted yet for this study

Summary

The purpose of this study is to investigate the effects of a multispecies probiotic on the function of the vagal nerve in patients with major depression and healthy participants in a single-center, randomized, placebo-controlled trial.

Conditions

  • Depressive Disorder, Major

Interventions

DIETARY_SUPPLEMENT

Multispecies-Probiotic

Participants in intervention group receive 2x3g of a multistrain probiotic containing Bifidobacterium bifidum W23, Bifidobacterium lactis W51, Bifidobacterium lactis W52, Lactobacillus acidophilus W22, Lactobacillus casei W56, Lactobacillus paracasei W20, Lactobacillus plantarum W62, Lactobacillus salivarius W24, Lactococcus lactis W19.

DIETARY_SUPPLEMENT

Placebo Supplement

Participants in the placebo group receive 2x3 gram of a placebo supplement not containing probiotic strains.

Sponsors & Collaborators

  • Allergosan

    collaborator UNKNOWN

  • Medical University of Graz

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2021-08-16
Primary Completion
2023-10-30
Completion
2023-10-30

Countries

  • Austria

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04772664 on ClinicalTrials.gov