Detection of Microdeletions in the Azoospermia Factor (AZF) Regions in Infertile Male Patients

NCT03497728 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 5000

Last updated 2022-01-26

No results posted yet for this study

Summary

In this prospective study, we used Multiplex ligation-dependent probe amplification and next-generation sequencing technology to detect AZF microdeletion types accurately in selected genetic locus, and made correlation analysis with clinical treatment results.

Conditions

  • Azoospermia or Severe Oligozoospermia

Sponsors & Collaborators

  • Anhui Provincial Hospital

    collaborator OTHER_GOV
  • Tang-Du Hospital

    collaborator OTHER
  • The Affiliated Hospital of Inner Mongolia Medical University

    collaborator OTHER
  • Henan Provincial People's Hospital

    collaborator OTHER
  • The First Affiliated Hospital of Anhui Medical University

    collaborator OTHER
  • The First Hospital of Jilin University

    collaborator OTHER
  • Reproductive & Genetic Hospital of CITIC-Xiangya

    lead OTHER

Principal Investigators

  • Yueqiu Tan · Reproductive & Genetic Hospital of CITIC-Xiangya

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-12-04
Primary Completion
2021-09-01
Completion
2021-12-01

Countries

  • China

Study Locations

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Read the full study record

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View NCT03497728 on ClinicalTrials.gov