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Effect of Age on Sperm Recovery of Microdissection Testicular Sperm Extraction in Nonobstructive Azoospermia Patients

NCT05958576 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 3104

Last updated 2023-07-24

No results posted yet for this study

Summary

Males with non-obstructive azoospermia (NOA) have an opportunity to obtain sperm by treatment with microdissection testicular sperm extraction (mTESE), gold-standard surgical technique for them. The overall sperm retrieval rate (SRR) of mTESE in NOA patients is about 50%, but the predictive factors of SRR remain were understudied, especially the effect of age. The purpose of this study was to explore the factors influencing the SRR of mTESE in NOA patients with different etiologies.

Methods: This observational study recruit NOA patients treated with their first mTESE. The stratified research was used to investigate SRR by dividing patients into seven groups based on etiology. The primary outcome was SRR. Multivariable logistic regression was used to analyze the factors influencing SRR.

Conditions

  • Non-obstructive Azoospermia

Sponsors & Collaborators

  • Peking University Third Hospital

    lead OTHER

Principal Investigators

  • Li Zhang, Ph.D · Peking University Third Hospital

Eligibility

Min Age
21 Years
Max Age
57 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2012-03-01
Primary Completion
2022-12-31
Completion
2023-03-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05958576 on ClinicalTrials.gov