Additional Low Voltage Area Ablation in Older Patients With Paroxysmal Atrial Fibrillation

Summary

The primary objective of this investigation is to compare the efficacy of two different AF ablation strategies in older patients with paroxysmal AF: Pulmonary vein isolation alone versus additional low-voltage substrate modification during sinus rhythm

Conditions

• Paroxysmal Atrial Fibrillation

Interventions

PROCEDURE

CPVI plus low-voltage substrate modification

CPVI plus low-voltage substrate modification in the left atrium during SR

PROCEDURE

CPVI alone

circumferential pulmonary vein isolation

Sponsors & Collaborators

• The Affiliated Hospital of Xuzhou Medical University

  collaborator OTHER

• First Affiliated Hospital of Wannan Medical College

  collaborator OTHER

• Second Affiliated Hospital of Nantong University

  collaborator OTHER

• Zhongda Hospital

  collaborator OTHER

• The Third Affiliated Hospital of Soochow University

  collaborator OTHER

• The Second Hospital of Hebei Medical University

  collaborator OTHER

• The First Affiliated Hospital of Soochow University

  collaborator OTHER

• Xuzhou Central Hospital, the Affiliated Xuzhou Hospital of Medical College of Southeast University

  collaborator UNKNOWN

• Air Force Military Medical University, China

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  lead OTHER

Principal Investigators

• Minglong Chen · The First Affiliated Hospital with Nanjing Medical University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Model

PARALLEL

Eligibility

Min Age

65 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2018-04-24

Primary Completion

2020-08-03

Completion

2021-08-17

Countries

• China

Study Locations