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Blueberries, Bananas, Exercise Recovery

NCT03445234 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2018-02-26

No results posted yet for this study

Summary

The PURPOSE of this study is to investigate the combined influence of 2-weeks blueberry ingestion and banana ingestion (during exercise) on performance and in mitigating metabolic perturbation, immune dysfunction, and increase in inflammation following a 75-km cycling time trial. We hypothesize that the combination of 2-weeks ingestion of blueberries (versus placebo) and acute ingestion of bananas (versus water alone) during 75-km cycling will:

1. Enhance performance.
2. Attenuate the magnitude of metabolic perturbation due to exercise (using a targeted panel of metabolites) which may be associated with increased plasma levels of beneficial gut-derived phenolics.
3. Attenuate post-exercise inflammation (as measured with cytokines, muscle damage markers, regulatory lipid mediators, ex-vivo monocyte cell cultures, and targeted immune proteins including S100A8 and S100A12).
4. Counter post-exercise downturns in innate immune function (natural killer cell lytic activity), and viral defense (using an ex-vivo cell culture with Hela cells).

Conditions

  • Inflammatory Response
  • Metabolic Disturbance
  • Immune Suppression

Interventions

DIETARY_SUPPLEMENT

Blueberry

26 g/day freeze-dried powder, 2 weeks duration

DIETARY_SUPPLEMENT

Placebo

Placebo powder

DIETARY_SUPPLEMENT

banana

Acute ingestion of bananas 0.2 g carb/kg every 15 min exercise with water

DIETARY_SUPPLEMENT

No banana

water only

Sponsors & Collaborators

  • Dole Food Company

    collaborator INDUSTRY

  • Appalachian State University

    lead OTHER

Principal Investigators

  • David C. Nieman, DrPH · Appalachian State Univ

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
55 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-09-11
Primary Completion
2017-12-15
Completion
2017-12-15

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03445234 on ClinicalTrials.gov