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Troponin Elevation After Major Noncardiac Surgery 2

NCT03408522 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 1000

Last updated 2019-01-16

No results posted yet for this study

Summary

Major adverse cardiac events (MACE) are a leading cause of mortality in patients undergoing noncardiac surgery. Patients with perioperative myocardial injury (PMI), defined as either myocardial infarction and lower elevations in cardiac troponin, are also at substantially increased risk of additional cardiac and noncardiac complications. Accordingly, it is plausible to assume that PMI negatively affects quality of life in terms of disability. The aim of this study is to investigate and compare the independent prognostic effects of the different PMI phenotypes (myocardial infarction and non-infarct troponin elevations) and noncardiac complications on disability in patients undergoing elective noncardiac surgery.

Conditions

  • Perioperative Myocardial Infarction
  • Disability
  • Perioperative/Postoperative Complications

Sponsors & Collaborators

  • University Health Network, Toronto

    collaborator OTHER

  • UMC Utrecht

    lead OTHER

Principal Investigators

  • Wilton A van Klei, MD PhD · prof. dr.

  • W. Scott Beattie, MD PhD FRCPC · prof. dr.

Eligibility

Min Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-01-29
Primary Completion
2019-06-30
Completion
2019-12-31

Countries

  • Canada
  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03408522 on ClinicalTrials.gov