MedTrace Logo

The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery

NCT05992961 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 558

Last updated 2023-08-18

No results posted yet for this study

Summary

Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury after non-cardiac surgery (MINS) and mortality. The majority of patients with MINS will not experience any symptoms, and thus MINS remains undetected without routine troponin measurements.

The investigators hypothesized that implementing surveillance with troponin I as a standard care might be useful as risk stratification, and that increased surveillance, examinations, and subsequent individually based medical interventions, might improve the outcomes for patients with MINS.

Conditions

  • Abdomen, Acute
  • Myocardial Injury After Non-cardiac Surgery
  • Troponin I
  • Myocardial Injury
  • Emergency Surgery

Interventions

DIAGNOSTIC_TEST

Troponin I

Troponin I were measured 6-12 hours postoperatively and on each of the succeeding four postoperative days for patients operated March 1, 2019, to February 28, 2021. Patients with increased troponin I levels were assessed regarding symptoms of myocardial ischaemia including electrocardiography. Each patient was individually assessed, and relevant treatment and follow-up were planned in collaboration between surgeons, cardiologists, and anaesthesiologists.

Sponsors & Collaborators

  • Nordsjaellands Hospital

    lead OTHER

Principal Investigators

  • Claus Anders TB Bertelsen, PhD, MD · Copenhagen University Hospital - North Zealand

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-01
Primary Completion
2021-02-28
Completion
2021-02-28

Countries

  • Denmark

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05992961 on ClinicalTrials.gov