Clinical and Economic Outcomes of High Sensitivity Troponin for no ST Elevation Myocardial Infarction in Patients With Chest Pain in Emergency Departments in Italy-An Observational Study

Summary

Myocardial infarction is one of the leading causes of death and disability worldwide. In addition to standard diagnostic methods, it has been shown that high-sensitivity cardiac troponin assays allow greater sensitivity in the diagnosis of myocardial infarction and assume a central role for both exclusion ("rule out") and confirmation ("rule in") of acute myocardial infarction , while allowing to reduce the time interval between ER admission and presumptive diagnosis.

Considering the relevance of this topic, we propose to conduct an observational study in real world clinical practice settings at Emergency Departments, aiming to evaluate clinical and economic aspects deriving from the use of the different quantitative assays of high-sensitivity cardiac troponin currently available in patients with suspected acute myocardial infarction and non-ST-elevation ECG (NSTEMI) on the admission, including time of diagnosis and number of laboratory and imaging tests performed.

Conditions

• NSTEMI - Non-ST Segment Elevation MI

Sponsors & Collaborators

• Azienda Ospedaliero Universitaria Maggiore della Carita

  collaborator OTHER

• Azienda Sanitaria Locale ASL 6, Livorno

  collaborator OTHER_GOV

• Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

  collaborator OTHER

• Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

  collaborator OTHER

• Ospedale Civile - Padova

  collaborator UNKNOWN

• S. Andrea Hospital

  collaborator OTHER

• Azienda Policlinico Umberto I

  collaborator OTHER

• San Carlo Public Hospital, Potenza, Italy

  collaborator OTHER

• Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari

  collaborator OTHER

• Policlinico Universitario, Catania

  collaborator OTHER

• Azienda Ospedaliera Sant'Anna

  collaborator OTHER

• Ospedale di Cattinara - Azienda Universitaria Integrata -Trieste

  collaborator UNKNOWN

• Abbott

  collaborator INDUSTRY

• Informapro Srl

  collaborator OTHER

• Marco Marchetti

  lead OTHER

Principal Investigators

• Marco Marchetti, MD · Istituto Superiore di Sanità

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-10-11

Primary Completion

2018-07-11

Completion

2019-06-15

Countries

• Italy

Study Locations