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Study of Peri-Articular Anaesthetic for Replacement of the Knee

NCT03326180 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 533

Last updated 2022-11-04

No results posted yet for this study

Summary

The clinical and cost effectiveness of peri-articular liposomal bupivacaine plus bupivacaine hydrochloride compared with bupivacaine hydrochloride alone for post-operative recovery after knee replacement surgery: A multi-centre, patient-blinded, randomised controlled trial.

Conditions

Interventions

DRUG

Liposomal bupivacaine

266mg/20ml vial of EXPAREL

DRUG

Bupivacaine hydrochloride

100mg/20ml 0.5% bupivacaine hydrochloride. Branded or generic, must be plain (cannot contain adrenaline/epinephrine)

Sponsors & Collaborators

  • University of Oxford

    collaborator OTHER

  • University of Leeds

    lead OTHER

Principal Investigators

  • Hemant Pandit · University of Leeds

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-03-29
Primary Completion
2021-02-28
Completion
2021-04-21
FDA Drug
Yes

Countries

  • United Kingdom

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03326180 on ClinicalTrials.gov