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Patient Controlled Epidural Analgesia Versus Local Infiltration Analgesia Following Knee Arthroplasty

NCT02478372 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 242

Last updated 2015-11-10

Study results available
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Summary

The purpose of this study was to determine if the method of peri-operative analgesia used following total Knee Replacement surgery affected the progress towards rehabilitation goals and to determine whether the analgesia had any impact on long term outcomes.

Conditions

Interventions

DRUG

Patient Controlled Epidural (PCEA)

Following the operation, 4ml of 0.25% levobupivacaine was administered and the catheter was connected to a PCEA. Self-medication with a bolus 2ml of 0.125% bupivacaine via the PCEA system with a lockout time of 15 minutes until the following morning (post-operative day one) when it was stopped.

DRUG

Local Infiltration Analgesia (LIA)

Subcutaneous infiltration during surgery using 200ml of 0.2% plain ropivacaine.

Sponsors & Collaborators

  • Glasgow Caledonian University

    collaborator OTHER

  • Golden Jubilee National Hospital

    lead OTHER_GOV

Principal Investigators

  • David A McDonald, BSc · Golden Jubilee National Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2010-04-30
Primary Completion
2011-08-31
Completion
2012-11-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02478372 on ClinicalTrials.gov