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Determinants of Formate Concentrations

NCT03305900 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1701

Last updated 2017-10-10

No results posted yet for this study

Summary

Formate is an important metabolite, serving as a donor of one-carbon groups to the intracellular tetrahydrofolate pool. However, little is known of its circulating concentrations or of their determinants. This study seeks to define formate levels and their determinants in a young, healthy population.

Serum formate will be measured in 1701 subjects from the Trinity Student Study. The subjects, males and females, aged 18 to 28 years, were enrolled at Trinity College, Dublin. Formate levels will be compared with other one-carbon metabolites, vitamin status, potential formate precursors, genetic polymorphisms, and lifestyle factors.

Conditions

  • Healthy

Interventions

OTHER

No Intervention

Cross-sectional study requiring a single serum sample

Sponsors & Collaborators

  • University of Dublin, Trinity College

    collaborator OTHER

  • Memorial University of Newfoundland

    lead OTHER

Principal Investigators

  • Anne Molloy, Ph.D. · University of Dublin, Trinity College

Eligibility

Min Age
18 Years
Max Age
28 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-12-01
Primary Completion
2013-11-26
Completion
2013-11-26

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03305900 on ClinicalTrials.gov