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Heart Failure and Aortic Stenosis Transcriptome

NCT03268135 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2025-04-30

No results posted yet for this study

Summary

This study is aimed to investigate the global transcriptome in order to determine the expression profile of messenger RNAs (mRNAs), as well as long noncoding- (lncRNAs) and micro noncoding-RNAs (miRNAs) in heart failure (HF) and in aortic stenosis (AS). The aim is to clarify their role in cardiac disease pathogenesis, as well as their potential as biomarkers. To this purpose, both tissue and blood specimens will be collected and patients will be compared to individuals not affected by cardiovascular diseases.

Conditions

Interventions

DIAGNOSTIC_TEST

measurement of RNAs

Sponsors & Collaborators

  • Ospedale San Raffaele

    collaborator OTHER

  • IRCCS Policlinico S. Donato

    lead OTHER

Principal Investigators

  • Fabio Martelli, Dr · IRCCS Policlinico S. Donato

Eligibility

Min Age
40 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-30
Primary Completion
2024-12-31
Completion
2027-12-31

Countries

  • Italy

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03268135 on ClinicalTrials.gov