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fMRI of Hypothalamic Responses to Taste, Temperature and Glucose

NCT03202342 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 16

Last updated 2017-06-28

No results posted yet for this study

Summary

The study will consist of five occasions with one week in between. BOLD signal intensity of the hypothalamus will be measured using fMRI. Measurements will be done before and after drinking 300 ml plain water or water to which glucose and/or ethyl butyrate will be added.

Conditions

  • Healthy

Interventions

OTHER

Water

Water, 300 ml, at room temperature

OTHER

Glucose

Water containing 50 g glucose, 300 ml, at room temperature

OTHER

Ethyl butyrate

Water containing ethyl butyrate (pineapple flavour) 300 ml, at room temperature

OTHER

Glucose + ethyl butyrate

Water containing 50 g glucose and ethyl butyrate (pineapple flavour) 300 ml, at room temperature

OTHER

Glucose + ethyl butyrate 0 C

Water containing 50 g glucose and ethyl butyrate (pineapple flavour) 300 ml, at 0 degrees centigrade

Sponsors & Collaborators

  • Leiden University Medical Center

    collaborator OTHER

  • Unilever R&D

    lead INDUSTRY

Principal Investigators

  • Jeroen van der Grond · Leiden University Medical Center

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
25 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2013-11-11
Primary Completion
2014-10-30
Completion
2014-10-30

Countries

  • Netherlands

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03202342 on ClinicalTrials.gov