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S. Aureus Decolonization in HPN Patients.

NCT03173053 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 63

Last updated 2022-05-31

No results posted yet for this study

Summary

This trial focusses on identifying the most effective and safe long-term S. aureus carriage decolonization strategy in home parenteral nutrition patients. Half of the participants will receive a quick and short systemic antibiotic treatment combined with topical treatment, while the other half will receive only topical treatment on a periodic basis.

Conditions

  • Staphylococcus Aureus
  • Motility Disorder

Interventions

DRUG

Doxycycline

tablet

DRUG

Trimethoprim

tablet

DRUG

Sulfamethoxazole/trimethoprim

tablet

DRUG

Clindamycin

tablet

DRUG

Clarithromycin

tablet

DRUG

Ciprofloxacin

tablet

DRUG

Fusidic Acid

tablet or ointment

DRUG

Rifampin

tablet

DRUG

Chlorhexidine

Mouthwash or bodywash

DRUG

Mupirocin

Nasal ointment

DRUG

Betadine

Shampoo

Sponsors & Collaborators

  • ZonMw: The Netherlands Organisation for Health Research and Development

    collaborator OTHER

  • Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

    collaborator OTHER

  • University College, London

    collaborator OTHER

  • Radboud University Medical Center

    lead OTHER

Principal Investigators

  • Joost PH Drenth, MD, PhD · Sponsor GmbH

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-02-08
Primary Completion
2021-10-14
Completion
2021-10-14

Countries

  • Denmark
  • Netherlands

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03173053 on ClinicalTrials.gov