Clindamycin as Antimicrobial Treatment for Streptococcus Spp. PeRiprosthetic Infection
NCT07335627 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 260
Last updated 2026-01-13
Summary
Clindamycin is an antibiotic with several advantages: high oral bioavailability and good bone and joint penetration. In France, it is a recommended drug for other types of Streptococcus spp. osteoarticular infections and can be used as an alternative to amoxicillin for periprosthetic infections, including when implants are retained.
The hypothesis of this study is that clindamycin is no less effective than other drugs commonly used to treat periprosthetic Streptococcus spp. infections.
The primary objective of this study is to evaluate the success rate of Streptococcus spp. periprosthetic joint infections treated with clindamycin compared to other antibiotic treatments.
Conditions
- Streptococcus Infection
Sponsors & Collaborators
-
University Hospital, Strasbourg, France
lead OTHER
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2025-02-21
- Primary Completion
- 2026-07-31
- Completion
- 2026-07-21
Countries
- France
Study Locations
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