Comparison of Four Different Supplementary Foods in the Treatment of Moderate Acute Malnutrition

Summary

The research seeks to determine the relative effectiveness and cost effectiveness of alternative supplementary foods in the treatment of moderate acute malnutrition (MAM) in normal program settings. The results of this study will guide decisions about what commodities to use in supplementary feeding programs in particular contexts and populations, and what factors need to be addressed to ensure maximum effectiveness in the treatment of moderate malnutrition.

Tufts University, Washington University in St. Louis, School of Medicine, Sierra Leone Ministry of Health and Sanitation (MoHS), Project Peanut Butter, Caritas Bo, World Food Programme (WFP), and the United States Agency for International Development (USAID) are collaborating to conduct an assessment of the effectiveness, cost, and cost-effectiveness of food aid commodities in treating moderate acute malnutrition (MAM) in young children. The study comparison is based on a targeted food delivery to children 6-59 months who are screened for MAM. Study participants will receive one of four approximately isoenergetic test foods:

1. Super Cereal Plus (SC+) with amylase
2. Corn-soy Blend Plus (CSB+) and fortified vegetable oil
3. Corn-soy Whey Blend (CSWB) and fortified vegetable oil (CSWB is a new product which is a modified version of CSB)
4. Ready-to-use Supplementary Food (RUSF, lipid-based)

Conditions

• Moderate Acute Malnutrition

Interventions

DIETARY_SUPPLEMENT

Supplementary Food

Supplementary food for treating MAM

Sponsors & Collaborators

• Washington University School of Medicine

  collaborator OTHER

• Project Peanut Butter

  collaborator OTHER

• Caritas Bo

  collaborator UNKNOWN

• Ministry of Health and Sanitation, Sierra Leone

  collaborator OTHER_GOV

• United Nations World Food Programme (WFP)

  collaborator OTHER

• United States Agency for International Development (USAID)

  collaborator FED

• Tufts University

  lead OTHER

Principal Investigators

• Beatrice Rogers, PhD · Tufts University

• Mark Manary, MD · Washington University School of Medicine

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Model

PARALLEL

Eligibility

Min Age

6 Months

Max Age

59 Months

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-04-11

Primary Completion

2018-11-24

Completion

2018-11-24

Countries

• Sierra Leone

Study Locations