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Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2

NCT03141619 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 500

Last updated 2023-12-26

No results posted yet for this study

Summary

This study is designed to test the hypothesis that poor cerebral perfusion during critical illness is a risk factor for acute and long-term neurological dysfunction among survivors. We use near-infrared spectroscopy to measure brain tissue oxygenation as a non-invasive surrogate marker for cerebral perfusion. Acute neurological dysfunction is defined as the presence of delirium, which is assessed using the Confusion Assessment Method-Intensive Care Unit (CAM-ICU). Chronic neurological dysfunction is defined as having quantitative impairments on robotic testing (KINARM robot) and traditional neuropsychological screening (Repeatable Battery for the Assessment of Neuropsychological Status).

Conditions

Sponsors & Collaborators

  • University Health Network, Toronto

    collaborator OTHER

  • Vancouver General Hospital

    collaborator OTHER

  • Western University, Canada

    collaborator OTHER

  • University of Ottawa

    collaborator OTHER

  • Université de Montréal

    collaborator OTHER

  • University of Calgary

    collaborator OTHER

  • University of Pittsburgh

    collaborator OTHER

  • Dr. Gordon Boyd

    lead OTHER

Principal Investigators

  • J. Gordon Boyd, MD, PhD · Queen's University

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-10-13
Primary Completion
2024-06-30
Completion
2025-06-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03141619 on ClinicalTrials.gov