Image Fusion of SPECT MPI and Fluoroscopy Venography to Guide LV Lead Placement for Improved CRT Response (GUIDE-CRT II)

Summary

CRT response will be significantly better using image fusion of SPECT MPI and fluoroscopy venogram to guide LV lead placement at the latest activation segment without scar than standard-of-care implantation.

Conditions

• Chronic Heart Failure

Interventions

OTHER

Image fusion of SPECT MPI and fluoroscopy venography

In this study, MPI-Fluoro Fusion tool is used to help the implanting physicians to precisely implant LV lead to the optimal/suboptimal venous segments in the guided group.

Sponsors & Collaborators

• Fu Wai Hospital, Beijing, China

  collaborator OTHER

• Shanghai Zhongshan Hospital

  collaborator OTHER

• Shanghai Chest Hospital

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• Xijing Hospital

  collaborator OTHER

• First Affiliated Hospital of Zhejiang University

  collaborator OTHER

• Sir Run Run Shaw Hospital

  collaborator OTHER

• First People's Hospital of Hangzhou

  collaborator OTHER

• Anhui Provincial Hospital

  collaborator OTHER_GOV

• The Affiliated Hospital of Xuzhou Medical University

  collaborator OTHER

• West China Hospital

  collaborator OTHER

• The First Affiliated Hospital of Dalian Medical University

  collaborator OTHER

• General Hospital of Shenyang Military Region

  collaborator OTHER

• Nanjing Medical University

  collaborator OTHER

• Subei People's Hospital of Jiangsu Province

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  lead OTHER

Principal Investigators

• Jiangang Zou, MD,Ph.D · The First Affiliated Hospital with Nanjing Medical University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

PARALLEL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2017-04-14

Primary Completion

2024-12-31

Completion

2025-05-31

Countries

• China

Study Locations