Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis

Summary

Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial ischemia. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the calibration of MCG analysis. This is a prospective single-center study aiming to build accurate analytical models of MCG to detect coronary lesions and myocardial necrosis. Coronary lesions are measured by coronary angiography (CAG) or coronary CTA, and are defined by both the stenosis degree and the computer-simulated fraction flow reserve. Myocardial necrosis is examined and quantified by cardiac MR. Healthy volunteers, chest pain patients who will receive CAG or CTA examination, and patients with acute myocardial infarction will be enrolled in this study.

Conditions

• Chest Pain, Acute Coronary Syndrome, Myocardial Infarction

Interventions

DEVICE

Magnetometer

inspection equipment for magnetocardiography

Sponsors & Collaborators

• Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

  collaborator OTHER

• Weifang People's Hospital

  collaborator OTHER

• Linyi People's Hospital

  collaborator OTHER

• Jining First People's Hospital

  collaborator OTHER

• The First Affiliated Hospital with Nanjing Medical University

  collaborator OTHER

• Second Affiliated Hospital, School of Medicine, Zhejiang University

  collaborator OTHER

• First Affiliated Hospital Xi'an Jiaotong University

  collaborator OTHER

• Chongqing Emergency Medical Center

  collaborator OTHER

• Guangdong Provincial Hospital of Traditional Chinese Medicine

  collaborator OTHER

• First People's Hospital of Hangzhou

  collaborator OTHER

• Qianfoshan Hospital

  collaborator OTHER

• Weihai Central Hospital

  collaborator OTHER

• Heze Municipal Hospital

  collaborator OTHER

• Qilu Hospital of Shandong University

  lead OTHER

Principal Investigators

• Yuguo Chen, Dr · Qilu Hospital of Shandong University

Study Design

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

SINGLE

Model

SINGLE_GROUP

Eligibility

Min Age

18 Years

Max Age

79 Years

Sex

ALL

Healthy Volunteers

Yes

Timeline & Regulatory

Start

2022-05-30

Primary Completion

2024-08-30

Completion

2024-12-30

Countries

• China

Study Locations