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Vascular Endothelial Function and Cardiac Resynchronization Response in Patients With Heart Failure

NCT02783716 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2023-01-18

No results posted yet for this study

Summary

The purpose of this research study is to determine the role of blood vessel endothelial function in heart failure and the effect of Cardiac Resynchronization Therapy (CRT) on heart and endothelial function.

Conditions

Interventions

PROCEDURE

Subcutaneous adipose tissue collection

During standard of care device implantation procedure, a small piece of fat tissue will be removed from the device pocket inside the chest

DIAGNOSTIC_TEST

Peripheral arterial tonometry (PAT)

Non-invasive testing for blood vessel function. Specially designed finger probes placed on the middle finger of each hand. Pulsatile volume changes of the distal digit inducing pressure alterations in the finger cuff will be sensed by pressure transducers and recorded. Endothelial function will be measured via a reactive hyperemia (RH)-PAT index (RHI)

Sponsors & Collaborators

Principal Investigators

  • Hon-Chi Lee, MD, PhD · Mayo Clinic

Study Design

Allocation
NON_RANDOMIZED
Purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-05-31
Primary Completion
2021-07-20
Completion
2021-07-20

Countries

  • United States

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02783716 on ClinicalTrials.gov