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Does Sevoflurane Cause Genomic Damage

NCT03109119 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 30

Last updated 2019-01-14

No results posted yet for this study

Summary

This study aims to find out if sevoflurane causes any cell damage to patients undergoing general anaesthesia. In case of any damage, the reversibility of the damage is also assessed. This is a prospective, comparative study carried out in all children scheduled for surgical repair of cleft lip or palate admitted in the Department of Plastic Surgery under Smile Train organisation ìn our hospital,who satisfy the inclusion and exclusion criteria.

Conditions

  • Anesthesia; Adverse Effect

Interventions

DRUG

Sevoflurane

The patients in the group S will be exposed to routine concentrations of sevoflurane during anaesthesia.

DRUG

Propofol

These patients will be induced with propofol 1.5 mg / kg and maintained with propofol infusion.

Sponsors & Collaborators

  • Jubilee Mission Medical College and Research Institute

    lead OTHER

Principal Investigators

  • Vigil Peter, MD · Jubilee Mission Medical College and Research Institute, Thrissur, India

Study Design

Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
6 Months
Max Age
12 Months
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2018-09-01
Primary Completion
2019-09-30
Completion
2019-12-31

Countries

  • India

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03109119 on ClinicalTrials.gov