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Salivary Therapeutic Drug Monitoring of Anti-Tuberculosis Drugs

NCT03080012 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 24

Last updated 2018-11-21

No results posted yet for this study

Summary

In tuberculosis patients, salivary concentrations will be compared to plasma/serum concentrations of several anti-tuberculosis drugs. If salivary concentrations correctly represent blood concentrations, this non-invasive sampling of saliva could be used for TDM of the tested drugs.

Conditions

Interventions

OTHER

Saliva sampling

Stimulated saliva samples are taken using cotton rolls.

OTHER

Plasma/serum sampling

Simultaneously with saliva sampling.

Sponsors & Collaborators

  • University Medical Center Groningen

    lead OTHER

Principal Investigators

  • Jan-Willem Alffenaar, PhD, PharmD · University Medical Center Groningen

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-03-07
Primary Completion
2018-05-02
Completion
2018-05-02

Countries

  • Netherlands

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03080012 on ClinicalTrials.gov