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Saliva and Dried Blood Spot Therapeutic Drug Monitoring for MDR-TB in Tanzania

NCT04124055 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 51

Last updated 2020-10-30

No results posted yet for this study

Summary

Dried blood spot and saliva samples are collected during multidrug resistant tuberculosis (MDR-TB) treatment to measure the drug concentration of levofloxacin. Feasibility of both analytical procedures in a high burdened setting is explored.

Conditions

  • MDR-TB

Interventions

DIAGNOSTIC_TEST

Therapeutic drug monitoring (TDM)

Saliva and dried blood spot samples are collected. Based on the measured drug concentration the dose can be adjusted

Sponsors & Collaborators

  • Kibong'oto Infectious Diseases Hospital

    collaborator OTHER_GOV

  • University of Virginia

    collaborator OTHER

  • Jan-Willem C Alffenaar

    lead OTHER

Principal Investigators

  • Stellah Mpagama, PhD · Kibong'oto ID hospital

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2019-09-24
Primary Completion
2019-12-15
Completion
2019-12-31

Countries

  • Tanzania

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04124055 on ClinicalTrials.gov