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The Transition From Blastomere to Trophectoderm Biopsy: Comparing Two PGS Strategies

NCT03062969 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 383

Last updated 2017-02-24

No results posted yet for this study

Summary

Shortly after the implementation of Comprehensive Chromosome Screening (CCS) techniques for Preimplantation Genetic Screening (PGS) came the transition in biopsy timing. Trophectoderm biopsy is meant to overcome the limitations of cleavage stage biopsy and single cell analysis.

Conditions

Interventions

PROCEDURE

Cleavage stage biopsy group

* intracytoplasmatic sperm injection (ICSI)- (Invitro Fertilization)IVF * Time lapse embryo culture * Cleavage stage biopsy * aCGH analysis * Fresh euploid embryo transfer

PROCEDURE

Trophectoderm biopsy group

* ICSI-IVF * Time lapse embryo culture * Day 3 zona pellucida opening * Trophectoderm biopsy * aCGH analysis * Frozen-thawed euploid embryo transfer

Sponsors & Collaborators

  • Fundacion Dexeus

    lead OTHER

Eligibility

Min Age
18 Years
Max Age
45 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-01
Primary Completion
2016-02-28
Completion
2017-01-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03062969 on ClinicalTrials.gov