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Mechanisms and Factors Responsible for the Inhibition of Transposons During Fetal Gonad Development in Humans

NCT02171845 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2022-07-08

No results posted yet for this study

Summary

This is a single-centre study over 36 months for the inclusion of 30 patients. The selection and inclusion of patients will take place according to the criterion of Medical Termination of Pregnancy at 4 different gestational ages (8-12 weeks of gestation (WG)), 13-16 WG, 17-23 WG and 25-35 WG. The tissue analysed will principally be the gonads, other somatic tissue will also be systematically harvested in parallel (liver and psoas muscle) for control purposes. The gonads will be subjected to molecular biology analyses destined to quantify the expression of transposons and their inhibitors.

Conditions

  • Medical Termination of Pregnancy
  • Voluntary Termination of Pregnancy

Interventions

OTHER

surgical biopsies

Sponsors & Collaborators

  • Centre Hospitalier Universitaire Dijon

    lead OTHER

Eligibility

Min Age
10 Weeks
Max Age
37 Weeks
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-01-29
Primary Completion
2027-01-31
Completion
2027-01-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02171845 on ClinicalTrials.gov