Vitamin A Status and Risk of Excessive Vitamin A Intake Among Urban Filipino Children

Summary

The goal of this study is to assess whether children 12-18 months of age who are exposed to multiple large-scale vitamin A programs, and who are likely to have vitamin A intakes above the tolerable upper intake level (UL), have higher total body vitamin A stores and biomarkers of excessive vitamin A status, compared to children 12-18 months of age who have adequate vitamin A intake.

Conditions

• Vitamin A Status

Interventions

OTHER

High VA intake, recent VAS

Children who are exposed to multiple VA programs, have received a high-dose VA supplement (VAS; 200,000 IU) in the past month, and are identified as being likely to have chronic excessive dietary VA intake.

OTHER

High VA intake

Children who are exposed to multiple VA programs, have received a high-dose VA supplement (200,000 IU) in the past 3-6 months, and are identified as being likely to have chronic excessive dietary VA intake.

OTHER

Low/adequate VA intake

Children who are not exposed to multiple VA programs, have received a high-dose VA supplement in the past 3-6 months, and are identified as being likely to have chronic low to adequate dietary VA intake.

Sponsors & Collaborators

• Newcastle University

  collaborator OTHER

• Penn State University

  collaborator OTHER

• Helen Keller International

  collaborator OTHER

• Food and Nutrition Research Institute, Philippines

  collaborator OTHER_GOV

• Global Alliance for Improved Nutrition

  collaborator OTHER

• Bill and Melinda Gates Foundation

  collaborator OTHER

• International Atomic Energy Agency

  collaborator OTHER_GOV

• University of California, Davis

  lead OTHER

Principal Investigators

• Georg Lietz · Newcastle University

Eligibility

Min Age

12 Months

Max Age

18 Months

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2016-08-31

Primary Completion

2017-03-31

Completion

2017-03-31

Countries

• Philippines

Study Locations