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T-PRF Provides Advantages on Periodontal Healing: A Split Mouth Clinical Study

NCT03027050 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 33

Last updated 2017-01-20

No results posted yet for this study

Summary

It was aimed to evaluate the contributions of T-PRF treatment combined with open flap debridement on biological markers in GCF and periodontal outcomes in chronic periodontitis patients. 29 patients (58 sites) with chronic periodontitis were treated either with autologous T-PRF with OFD or OFD alone. GCF growth factor levels and relative RANKL/OPG ratio at baseline and 2, 4 and 6 weeks postoperatively were analyzed, and clinical parameters such as probing depth (PD), relative attachment level (RAL) and gingival margin level (GML) at baseline and 9 months after surgery were compromised.

Conditions

  • Periodontitis
  • Periodontal Attachment Loss

Interventions

PROCEDURE

T-PRF

Applied for treatment of periodontal bone loss.

PROCEDURE

Open Flap Debridement alone

Sponsors & Collaborators

  • Ataturk University

    lead OTHER

Principal Investigators

  • Taner Arabacı · Ataturk University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2015-11-30
Primary Completion
2016-06-30
Completion
2016-11-30

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03027050 on ClinicalTrials.gov