MRS and 11C-methionine PET/CT in the Diagnosis of Glioma
NCT03009318 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100
Last updated 2018-04-09
Summary
MET PET and MRS are often performed as imaging tool for the differential diagnosis of gliomas. But both techniques have limitations causing misdiagnosis; thus, the investigators tried to combine these two imaging tools to study whether the combination of MET PET and MRS could raise the diagnosis ability of the radiological diagnosis of gliomas.
Conditions
Interventions
- OTHER
-
tumors are confirmed by surgery and pathology
Each patient undergoes both MRS and MET PET scan before surgery. The lesion will be considered as a glioma when either MRS or MET PET results indicated the diagnosis. Pathologic diagnosis will be performed to confirm the final diagnosis.
Sponsors & Collaborators
-
Huashan Hospital
lead OTHER
Principal Investigators
-
Dongxiao Zhuang, Professor · Huashan Hospital, Sudan University
Study Design
- Allocation
- NA
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2012-01-31
- Primary Completion
- 2016-09-30
- Completion
- 2017-12-31
Countries
- China
Study Locations
More Related Trials
-
[11C]Acetate PET in Patients With Glioma
NCT02986815 ·Status: TERMINATED ·Phase: NA
-
Combined O-(2-[18F]Fluoroethyl)-L-tyrosine (FET) Positron Emission Tomography (PET) and Simultaneous Magnetic Resonance Imaging (MRI) Follow-up in Re-irradiated Recurrent Glioblastoma Patients
NCT01579253 ·Status: UNKNOWN
-
FET-PET for Diagnosis and Monitoring in Patients With Low Grade Glioma
NCT01089244 ·Status: UNKNOWN
-
[18F]BF3-BPA Injection for PET Imaging Study of Gliomas in the Brain
NCT06148207 ·Status: RECRUITING ·Phase: NA
-
68Ga-BNOTA-PRGD2 PET/CT in Diagnosis and Evaluation of Glioma
NCT01801371 ·Status: UNKNOWN ·Phase: EARLY_PHASE1
-
Usefulness of Therapy Monitoring by Means of [(18)F]Fluoroethyltyrosine-Positron Emission Tomography (FET-PET) in Glioblastoma Multiforme Patients
NCT01089868 ·Status: COMPLETED
-
PET (FDG)-MR Imaging for the Adult Patients Presented With Brain Tumor
NCT02071017 ·Status: UNKNOWN
-
The Efficacy of APT Magnetic Resonance Imaging in Predicting the Efficacy of Bevacizumab in Recurrent Malignant Gliomas
NCT03180697 ·Status: UNKNOWN
-
MR Elastography in Intracranial Lesions: Feasibility & Accuracy
NCT06916715 ·Status: ACTIVE_NOT_RECRUITING
-
Multimodality Imaging Combined With Multiple Targets Pathological Examination for Detecting of Biological Borders of Gliomas: a Clinical Application Study
NCT02941302 ·Status: UNKNOWN ·Phase: NA
-
68Ga-citrate PET/MR Imaging for Glioma
NCT03335280 ·Status: TERMINATED
-
MRI in High-Grade Glioma Patients Undergoing Chemoradiation
NCT05212272 ·Status: RECRUITING ·Phase: NA
-
Magnetic Resonance Imaging in Determining Extent of Cancer in Patients With Newly Diagnosed Glioma
NCT00005082 ·Status: COMPLETED ·Phase: NA
-
68Ga-NOTA-RM26 PET/CT in Glioma Patients
NCT06412952 ·Status: RECRUITING ·Phase: EARLY_PHASE1
-
Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors
NCT00870129 ·Status: RECRUITING ·Phase: NA
-
Intraoperative Rapid Diagnosis of Glioma Based on Fusion of Magnetic Resonance and Ultrasound Imaging
NCT05656053 ·Status: ACTIVE_NOT_RECRUITING
-
Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion
NCT05990244 ·Status: RECRUITING ·Phase: NA
-
Evaluating Tumor Pseudoprogression With FLT-PET and MRI
NCT01105988 ·Status: TERMINATED ·Phase: EARLY_PHASE1
-
fMRI Reveal Functional Preservation in Glioma Peritumoral Edema
NCT07343492 ·Status: COMPLETED
-
Multimodal Diagnostic Assessment of Cerebral Gliomas With FET & FCH PET/CT, and Magnetic Resonance Imaging/Spectroscopy
NCT00939315 ·Status: COMPLETED
-
Study About the Validity of MRS-guided Resection on Prognosis High-grade Glioma Gliomas
NCT02795364 ·Status: UNKNOWN ·Phase: NA
-
Amino Acid PET to Assess the Efficacy of IDH Inhibitor Treatments for IDH Mutated Gliomas
NCT07017790 ·Status: NOT_YET_RECRUITING
-
The Utility of 18F-DOPA-PET in the Treatment of Recurrent High-grade Glioma
NCT03242824 ·Status: COMPLETED ·Phase: PHASE2
-
PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)
NCT01800032 ·Status: COMPLETED
-
18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas
NCT02175745 ·Status: TERMINATED ·Phase: NA