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Magnetic Resonance Elastography in Glioma: Exploring Tumor Stiffness and Adhesion

NCT05990244 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 100

Last updated 2025-12-02

No results posted yet for this study

Summary

this study will investigate the relationship between tumor stiffness and adhesion in gliomas using MRE. By utilizing preoperative MRE and Intraoperative neuronavigation, followed by comprehensive molecular pathology analysis, we aim to explore the correlation of tumor stiffness and adhesion with molecular and genetic characteristics of gliomas. Additionally, the predictive value of MRE in terms of pathological staging and prognosis will be determined. This research may pave the way for improved clinical decision-making, personalized treatment approaches, and more accurate clinical trials for glioma patients.

Conditions

Interventions

DIAGNOSTIC_TEST

Magnetic Resonance Elastography

Undergo MRE and routine MRI

PROCEDURE

Assessment and Recording

Undergo recording of tumor stiffness during surgery and molecular pathological classification through genetic analysis

Sponsors & Collaborators

  • Shengjing Hospital

    lead OTHER

Principal Investigators

  • Yu Shi, MD · Shengjing Hospital

  • Anhua Wu, MD · Shengjing Hospital

  • Wen Cheng, MD · Shengjing Hospital

  • Xiufang A( Ren, MD · Shengjing Hospital

Study Design

Allocation
NA
Purpose
DIAGNOSTIC
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2017-01-01
Primary Completion
2026-07-01
Completion
2027-07-01

Countries

  • China

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05990244 on ClinicalTrials.gov