18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

Summary

To evaluate 18F-FDOPA PET obtained from PET/CT or PET/MRI imaging in patients with newly diagnosed or recurrent gliomas.

Conditions

• Adult Anaplastic Ependymoma
• Adult Anaplastic Oligodendroglioma
• Adult Brain Stem Glioma
• Adult Diffuse Astrocytoma
• Adult Giant Cell Glioblastoma
• Adult Glioblastoma
• Adult Gliosarcoma
• Adult Mixed Glioma
• Adult Oligodendroglioma
• Adult Pilocytic Astrocytoma
• Adult Pineal Gland Astrocytoma
• Adult Subependymal Giant Cell Astrocytoma
• Childhood High-grade Cerebellar Astrocytoma
• Childhood High-grade Cerebral Astrocytoma
• Childhood Low-grade Cerebellar Astrocytoma
• Childhood Low-grade Cerebral Astrocytoma
• Recurrent Adult Brain Tumor
• Recurrent Childhood Anaplastic Astrocytoma
• Recurrent Childhood Anaplastic Oligoastrocytoma
• Recurrent Childhood Anaplastic Oligodendroglioma
• Recurrent Childhood Brain Stem Glioma
• Recurrent Childhood Cerebellar Astrocytoma
• Recurrent Childhood Cerebral Astrocytoma
• Recurrent Childhood Diffuse Astrocytoma
• Recurrent Childhood Fibrillary Astrocytoma
• Recurrent Childhood Gemistocytic Astrocytoma
• Recurrent Childhood Giant Cell Glioblastoma
• Recurrent Childhood Glioblastoma
• Recurrent Childhood Gliomatosis Cerebri
• Recurrent Childhood Gliosarcoma
• Recurrent Childhood Oligoastrocytoma
• Recurrent Childhood Oligodendroglioma
• Recurrent Childhood Pilomyxoid Astrocytoma
• Recurrent Childhood Protoplasmic Astrocytoma
• Recurrent Childhood Subependymal Giant Cell Astrocytoma
• Recurrent Childhood Visual Pathway and Hypothalamic Glioma
• Recurrent Childhood Visual Pathway Glioma
• Untreated Childhood Anaplastic Astrocytoma
• Untreated Childhood Anaplastic Oligoastrocytoma
• Untreated Childhood Anaplastic Oligodendroglioma
• Untreated Childhood Brain Stem Glioma
• Untreated Childhood Cerebellar Astrocytoma
• Untreated Childhood Cerebral Astrocytoma
• Untreated Childhood Diffuse Astrocytoma
• Untreated Childhood Fibrillary Astrocytoma
• Untreated Childhood Gemistocytic Astrocytoma
• Untreated Childhood Giant Cell Glioblastoma
• Untreated Childhood Glioblastoma
• Untreated Childhood Gliomatosis Cerebri
• Untreated Childhood Gliosarcoma
• Untreated Childhood Oligoastrocytoma
• Untreated Childhood Oligodendroglioma
• Untreated Childhood Pilomyxoid Astrocytoma
• Untreated Childhood Protoplasmic Astrocytoma
• Untreated Childhood Subependymal Giant Cell Astrocytoma
• Untreated Childhood Visual Pathway and Hypothalamic Glioma
• Untreated Childhood Visual Pathway Glioma

Interventions

DRUG

18F-fluoro-dihydroxyphenylalanine

Administered intravenously (IV)

PROCEDURE

Positron emission tomography (PET)

Component of an 18F-FDOPA PET/CT or PET/MRI scan

PROCEDURE

Computed tomography (CT)

Component of an 18F-FDOPA PET/CT

PROCEDURE

Magnetic resonance imaging

Component of an 18F-FDOPA PET/MRI

Sponsors & Collaborators

• National Cancer Institute (NCI)

  collaborator NIH

• Erik Mittra

  lead OTHER

Principal Investigators

• Erik Mittra, MD, PhD · Stanford University Hospitals and Clinics

Study Design

Allocation

NA

Purpose

DIAGNOSTIC

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Min Age

16 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2014-12-31

Primary Completion

2015-08-31

Completion

2015-12-31

Countries

• United States

Study Locations