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Intrathecal Morphine Analgesia vs. Continuous Epidural Analgesia vs. Systemic Analgesia in Colorectal Surgery.

NCT03007121 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 75

Last updated 2019-01-31

No results posted yet for this study

Summary

The purpose of this study is to determine which postoperative analgesia is optimal after colorectal surgery. The investigators will compare intrathecal morphine, continuous epidural analgesia and standard systemic analgesia. All patients will have the possibility to administer themselves intravenous morphine as needed.

Conditions

  • Analgesia, Patient-Controlled
  • Epidural Analgesia
  • Anesthesia; Spinal
  • Morphine
  • Surgery, Colorectal
  • Intravenous Drug Delivery Systems

Interventions

DRUG

Morphine intrathecal

Administration of intrathecal injection of 0.3 mg preservative-free morphine in 3 ml NS

DRUG

Bupivacaine + Sufentanil epidural

Continuous epidural infusion of a mixture containing in 1 ml bupivacaine 0,125% and sufentanil 0,4 mcg at 8 ml/h.

DRUG

Morphine intravenous

Patiernt-controlled i.v. analgesia with morphine

Sponsors & Collaborators

  • Charles University, Czech Republic

    lead OTHER

Principal Investigators

  • Jiri Malek, M.D. · 3rd Medical Faculty, Charles University and University Hiospital Kralovske Vinohrady

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2017-04-10
Primary Completion
2018-12-14
Completion
2018-12-17

Countries

  • Czechia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03007121 on ClinicalTrials.gov