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Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients

NCT02043366 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 180

Last updated 2016-01-08

Study results available
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Summary

Purpose:

To explore and compare antihyperalgesic effects of butorphanol, flurbiprofen axetil, and a combination of both received before anesthesia induction.

To evaluate and examine the incidence of adverse effects with the purpose of selecting the optimum dose.

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Conditions

Interventions

DRUG

Normal Saline

Normal Saline is intravenously administrated before anesthesia induction

DRUG

Butorphanol

Butorphanol is intravenously administrated

DRUG

Flurbiprofen axetil

Flurbiprofen axetil is intravenously administrated

DRUG

Remifentanil

Remifentanil is intravenously administrated

DRUG

Sufentanil

Sufentanil is intravenously administrated

Sponsors & Collaborators

  • Tianjin Medical University General Hospital

    lead OTHER

Principal Investigators

  • Guolin Wang, MD · Tianjin Medical University General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
20 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-02-28
Primary Completion
2015-06-30
Completion
2015-08-31

Countries

  • China

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02043366 on ClinicalTrials.gov