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Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial

NCT03000413 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 45

Last updated 2024-05-21

No results posted yet for this study

Summary

Despite few scientific evidence that could support the use of ketamine in adult patients undergoing acute bronchospasm requiring mechanical ventilation (MV), ketamine is largely employed in this setting. The aim of this study is therefore assess more definitively the real benefit of using ketamine in patients with severe bronchospasm, requiring ICU stay and need for MV in order to establish or refute the use of this drug as "standard therapy" in these cases.

Conditions

  • Critical Illness
  • Asthma
  • Bronchospasm

Interventions

DRUG

Ketamine

Active treatment

DRUG

Fentanyl

Sponsors & Collaborators

  • Hospital Nossa Senhora da Conceicao

    lead OTHER

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-06-04
Primary Completion
2017-06-16
Completion
2018-01-29

Countries

  • Brazil

Study Locations

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Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03000413 on ClinicalTrials.gov