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Nifedipine GITS and Amlodipine Besylate on Recovery of Blood Pressure Rhythm and Arterial Stiffness

NCT02940548 · Status: TERMINATED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 99

Last updated 2022-04-29

No results posted yet for this study

Summary

This trial evaluates the effects of Nifedipine GITS and Amlodipine besylate on blood pressure rhythm restoration and arterial stiffness in young and middle-aged non-dipper hypertensives. Half of participants will receive Nifedipine GITS, half of half will take medicine in the morning or at night. While the other half participants will take amlodipine besylate, whom will also be assigned taking medicine in the morning or at night. Ambulatory blood pressure monitoring and arterial stiffness examination will be performed before and after pharmaceutical intervention.

Conditions

Interventions

DRUG

Nifedipine GITS

Nifedipine GITS 30\~60mg/day for 8 weeks

DRUG

Amlodipine besylate

Amlodipine besylate 5\~10mg/day for 8 weeks

Sponsors & Collaborators

  • Bayer

    collaborator INDUSTRY

  • Jing Liu

    lead OTHER

Principal Investigators

  • Jing Liu, M.D. · Peking University People's Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-12-31
Primary Completion
2020-12-31
Completion
2020-12-31

Countries

  • China

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02940548 on ClinicalTrials.gov