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REducing Blood Pressure Variability in Essential Hypertension With RAmipril vErsus Nifedipine GITS Trial

NCT02499822 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 168

Last updated 2021-09-30

No results posted yet for this study

Summary

The purpose of this study is

1. to compare the effects of nifedipine GITS and ramipril on blood pressure variability in subjects with elevated blood pressure variability.
2. to assess whether the degree of treatment-induced changes in blood pressure variability, is related to the degree of regression (or progression) of organ damage in heart, kidneys and carotid arteries.

Conditions

Interventions

DRUG

Nifedipine GITS

Commercially available drug formulations are used. Study medication will be assumed in a single morning (7-10 a.m.) administration per os.

DRUG

Ramipril

Commercially available drug formulations are used. Study medication will be assumed in a single morning (7-10 a.m.) administration per os.

Sponsors & Collaborators

  • Bayer

    collaborator INDUSTRY

  • Istituto Auxologico Italiano

    lead OTHER

Principal Investigators

  • Gianfranco Parati, MD · Istituto Auxologico Italiano - Milan, Italy

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
PARALLEL

Eligibility

Min Age
35 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-10-31
Primary Completion
2020-07-03
Completion
2020-11-01

Countries

  • China
  • Greece
  • Italy

Study Locations

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Entities

Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02499822 on ClinicalTrials.gov