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Role of Comorbidities in Chronic Heart Failure Study

NCT02922478 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 205

Last updated 2019-06-24

No results posted yet for this study

Summary

This study aims to create a database of patients with stable and chronic heart failure with comprehensive assessment of bone, skeletal and vascular status. RoC-HF will facilitate cross-sectional and, eventually, longitudinal mechanistic epidemiological analyses to disentangle the role of the bone- vascular axis in chronic heart failure. Blood and urine samples will be stored to facilitate future biomarker analyses.

Conditions

Interventions

RADIATION

X-ray of the spine

Every participant will undergo X-ray of the spine so that vertebral fractures can be quantified using the Genant score.

PROCEDURE

Ambulatory blood pressure monitoring (ABPM)

ABPM will be performed using the brachial, oscillometric, automated self-measurement mobil-O-Graph device (I.E.M. GmbH, Stolberg, Germany) with integrated ARCSolver®-Software (Austrian Institute of Technology Wien).

RADIATION

Dual X-ray absorptiometry

Individual bone mineral density and T-Score will be determined by X-ray absorptiometry.

PROCEDURE

Non-invasive procedures

Other non-invasive study procedures include structured patient interview, sampling of blood, buffy coat and spot urine (including biobanking), electrocardiogram, pulse wave velocity and analysis, transthoracic echocardiography, 4-meter gait speed test, hand grip test, questionnaires

Sponsors & Collaborators

  • Medical University of Graz

    lead OTHER

Principal Investigators

  • Nicolas Verheyen, MD · Medical University of Graz

  • Klemens Ablasser, MD · Medical University of Graz

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2016-09-30
Primary Completion
2018-12-20
Completion
2018-12-20

Countries

  • Austria

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02922478 on ClinicalTrials.gov