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Prognostic Impact of Noncardiac Comorbidities in Heart Failure Patients

NCT02946476 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 2314

Last updated 2016-10-27

No results posted yet for this study

Summary

To better understand the public health prognostic impact of noncardiac chronic illnesses, we explored the attributable risk of noncardiac comorbidities on outcomes between heart failure patients with reduced ejection fraction (HFREF) and heart failure patients with preserved ejection fraction (HFpEF) in a large contemporary heart failure (HF) population The adjusted hazard ratio (HR) and the population attributable risk were used to compare the contributions of 15 noncardiac comorbidities to adverse outcome. The comorbidities that contributed to high attributable risk were: anemia, chronic kidney disease, chronic obstructive pulmonary disease, diabetes mellitus, and peripheral artery disease. These findings were similar for HFrEF and HFpEF groups. Interaction analysis confirmed similar results.

Conditions

  • Heart Failure, Diastolic
  • Heart Failure, Systolic

Interventions

OTHER

prognostic impact of non cardiac comorbidities

Sponsors & Collaborators

  • Ospedale Maggiore Di Trieste

    lead OTHER

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-11-30
Primary Completion
2013-12-31
Completion
2014-12-31

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02946476 on ClinicalTrials.gov