Correlation Between PET and Advanced MRI in Multiple Sclerosis
NCT02869360 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 14
Last updated 2019-10-03
Summary
Traditional Magnetic Resonance Imaging (MRI) in Multiple Sclerosis (MS) has enabled clinicians to measure disease activity but there are inherent limitations. Clinical/radiographic dissociation can be seen in some patients and the abnormalities are not specific.
This pilot study is an opportunity to determine the relationship between quantitative advanced MRI measures and OCT with PET measurements of microglial activation and myelin health.
Conditions
Sponsors & Collaborators
-
Teva Pharmaceuticals USA
collaborator INDUSTRY -
University of British Columbia
lead OTHER
Eligibility
- Min Age
- 18 Years
- Max Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2016-10-31
- Primary Completion
- 2019-10-02
- Completion
- 2019-10-02
Countries
- Canada
Study Locations
More Related Trials
-
Magnetic Resonance Imaging to Detect Brain Damage in Patients With Multiple Sclerosis
NCT00393588 ·Status: COMPLETED
-
Molecular Imaging of NET Using [C-11]MRB-PET in MS
NCT03207464 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases
NCT02649985 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Macromolecular Imaging of White and Gray Matter Pathology in Multiple Sclerosis
NCT04415372 ·Status: ENROLLING_BY_INVITATION
-
Contrast-enhanced 3D T1-weighted Gradient-echo Versus Spin-echo 3 Tesla MR Sequences in the Detection of Active Multiple Sclerosis Lesions
NCT03268239 ·Status: COMPLETED ·Phase: NA
-
Quantitative Imaging and Proton Spectroscopy in Multiple Sclerosis
NCT01226654 ·Status: TERMINATED ·Phase: NA
-
MR Perfusion Imaging and Hypercapnia (Increased Carbon Dioxide) to Study New Blood Vessel Formation in Multiple Sclerosis
NCT00064909 ·Status: COMPLETED
-
PET Imaging in Chronic Traumatic Encephalopathy
NCT02211820 ·Status: COMPLETED
-
Brain Peripheral Benzodiazepine Receptors in Patients With Multiple Sclerosis
NCT00432900 ·Status: COMPLETED ·Phase: PHASE1
-
Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis
NCT00563537 ·Status: UNKNOWN ·Phase: PHASE1
-
Advanced MRI Applications for Mild Traumatic Brain Injury
NCT02070588 ·Status: TERMINATED ·Phase: NA
-
Additional Positron Emission Tomography (PET) Scan of Brain in Patients Undergoing PET Scan for Diseases Unrelated to Brain
NCT00729092 ·Status: COMPLETED
-
Clinical Evaluation of an Integrated PET/MRI System
NCT02071706 ·Status: COMPLETED ·Phase: NA
-
Magnetic Resonance (MR) Spectroscopy and Diffusion Tensor Imaging in Determining Brain Injury and Subsequent Clinical Outcome in Patients of Moderate Brain Trauma
NCT00760903 ·Status: WITHDRAWN
-
Accurate Diagnosis of Multiple Sclerosis Using PET/MR
NCT04521439 ·Status: COMPLETED ·Phase: NA
-
Molecular Cerebral Imaging in Incipient Dementia (MCI-ID) II
NCT02317250 ·Status: WITHDRAWN ·Phase: PHASE3
-
Study for the Evaluation of the Feasibility of Applying Advanced MRI Scanning in Clinical Practice
NCT03232463 ·Status: ENROLLING_BY_INVITATION
-
Evaluation of [18F] PBR06 and PET as a Marker of Inflammation in Subjects With Neurological Conditions
NCT01028209 ·Status: TERMINATED ·Phase: PHASE1
-
Study by Magnetic Resonance Imaging in the Progressive Forms of Multiple Sclerosis
NCT02580669 ·Status: TERMINATED ·Phase: NA
-
Investigation of GM Pathology Using Ultra High Field (7T) MRI Scanner
NCT01805986 ·Status: UNKNOWN
-
Differentiating Recurrent Brain Tumor Versus Radiation Injury Using MRI
NCT00760409 ·Status: COMPLETED
-
Metabolic Imaging of Neurological Disease
NCT06900244 ·Status: ENROLLING_BY_INVITATION
-
Advanced MRI Applications for Mild Traumatic Brain Injury-Phase 2
NCT02556177 ·Status: COMPLETED ·Phase: NA
-
PET-MRI in Chronic Traumatic Brain Injury (CTBI)
NCT03241732 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Ultrahigh Field Body MR Imaging
NCT02236143 ·Status: ENROLLING_BY_INVITATION