Cerebral Energy State in Cardiac Surgery
NCT02846818 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10
Last updated 2016-07-27
Summary
Impaired cerebral function remains an important complication of cardiopulmonary bypass (CPB) during cardiac surgery. The aim of the present study is to investigate whether the lactate to pyruvate (LP) ratio obtained by microdialysis (MD) of the cerebral venous outflow reflects a derangement of global cerebral energy state during cardiopulmonary bypass.
Conditions
- Postoperative; Dysfunction Following Cardiac Surgery
Interventions
- PROCEDURE
-
Microdialysis
Extracerebral MD catheters were positioned in a retrograde direction in the internal jugular vein.
Sponsors & Collaborators
-
Odense University Hospital
lead OTHER
Principal Investigators
-
Palle Toft, Professor · Odense University Hospital
Study Design
- Allocation
- RANDOMIZED
- Purpose
- DIAGNOSTIC
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Min Age
- 60 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2015-02-28
- Primary Completion
- 2015-04-30
- Completion
- 2015-05-31
Countries
- Denmark
Study Locations
More Related Trials
-
Cerebral Autoregulation Monitoring During Cardiac Surgery
NCT00981474 ·Status: COMPLETED ·Phase: NA
-
Assessment of Cerebral Blood Flow Asymmetry in Cardiac Surgery Patients Undergoing Hypothermic Circulatory Arrest
NCT03215589 ·Status: TERMINATED
-
Preoperative Evaluation of Microcirculation for Prediction of Complications After Cardiac Surgery
NCT03631797 ·Status: COMPLETED ·Phase: NA
-
Predictive and Prognostic Value of Cellular Dysoxia Markers After Cardiac Surgery With Extracorporeal Circulation
NCT03107572 ·Status: COMPLETED
-
Brain Tissue Oxygen Saturation and Blood Transfusion in Cardiac Surgery
NCT00879463 ·Status: COMPLETED ·Phase: NA
-
Metabolic Fluid Responsiveness in Children
NCT07255469 ·Status: RECRUITING
-
In Situ Exploration of Vascular Function in Vasoplegic Shock Following Cardiac Surgery With Cardiopulmonary Bypass
NCT06318689 ·Status: RECRUITING
-
Norepinephrine Infusion During Cardiopulmonary Bypass
NCT04312971 ·Status: COMPLETED ·Phase: NA
-
Fluid Infusion During Breast Surgery
NCT00431743 ·Status: UNKNOWN ·Phase: PHASE4
-
Glycocalyx Monitoring in Major Abdominal Surgery
NCT06285526 ·Status: COMPLETED
-
Association of the Arteriovenous Difference in Carbon Dioxide and Its Relation to the Difference in Arteriovenous Oxygen Content With the Occurrence of Postoperative Complication
NCT03914976 ·Status: COMPLETED
-
Development of Ketoacidosis During the Perioperative Period: an Observational Study 'The DKAP Study'
NCT05225467 ·Status: COMPLETED
-
Remote Ischemic Preconditioning During Cardiopulmonary Bypass
NCT03723993 ·Status: WITHDRAWN ·Phase: NA
-
Microvascular Reactivity in Cardiac Surgery
NCT04759222 ·Status: COMPLETED
-
Perfusion Pressure Cerebral Infarction Trial (PPCI)
NCT02185885 ·Status: COMPLETED ·Phase: NA
-
The Influence of Preoperative Cardiopulmonary Capacity on the Perioperative Lactate Level
NCT01819337 ·Status: COMPLETED
-
Wireless Assessment of Respiratory and Circulatory Distress
NCT03491137 ·Status: COMPLETED
-
Hypertension and Cerebrovascular Hemodynamics in General Anaesthesia
NCT06855407 ·Status: RECRUITING ·Phase: NA
-
Prognostic Value of Peak Lactate During Cardiopulmonary Bypass in Adult Cardiac Surgeries
NCT03934892 ·Status: COMPLETED
-
Pontos-Central Venous Pressure and Cardiac Surgery
NCT03423420 ·Status: COMPLETED
-
ΔvapCO2 / Cav02 Ratio as a Prognostic Marker and Predictor of Complications After Cardiac Surgery
NCT02876406 ·Status: UNKNOWN
-
Predicting Cerebrovascular Adverse Events Post Cardiac Surgery
NCT05786274 ·Status: RECRUITING ·Phase: NA
-
Mean Arterial Pressure After Out-of-hospital Cardiac Arrest
NCT05486884 ·Status: RECRUITING ·Phase: NA
-
Prevention of Myocardial Injury in Non-cardiac Surgery
NCT02344797 ·Status: COMPLETED ·Phase: NA
-
Carotid Flow Time Measurement Guided Fluid Management During Spinal Anesthesia
NCT03734497 ·Status: WITHDRAWN ·Phase: NA